Andy Williams

Andy Williams, the affable, boyishly handsome crooner who defined both easy listening and wholesome, easygoing charm for many American pop music fans in the 1960s, most notably with his signature song, “Moon River,” died on Tuesday night at his home in Branson, Mo. He was 84 and also had a home in La Quinta, Calif.

The cause was cancer, his publicist, Paul Shefrin, said. Mr. Williams, who had continued to perform until last year, announced in November that he had bladder cancer.

“Moon River” was written by Henry Mancini and Johnny Mercer, and Audrey Hepburn introduced it in the 1961 film “Breakfast at Tiffany’s,” but it was Mr. Williams who made the song indisputably his own when he sang it at the 1962 Academy Awards ceremony and titled a subsequent album after it. When he built a theater in Branson, he named it the Andy Williams Moon River Theater.

“Moon River” became the theme song for his musical-variety television series “The Andy Williams Show,” which, along with his family-oriented Christmas TV specials, made him a household name.

“The Andy Williams Show” ran on NBC from 1962 to 1971 and won three Emmy Awards for outstanding variety series. But its run also coincided with the social and cultural upheavals of the 1960s, and with a lineup of well-scrubbed acts like the Osmond Brothers (whom Mr. Williams introduced to national television) and established performers like Judy Garland and Bobby Darin, the show, at least to many members of a younger, more rebellious generation, was hopelessly square — the sort of entertainment their parents would watch.

Despite that image, “The Andy Williams Show” was not oblivious to the cultural moment. Its guests also included rising rock acts like Elton John and the Mamas and the Papas, and its offbeat comedy skits, featuring characters like the relentless Cookie Bear and the Walking Suitcase, predated similar absurdism on David Letterman’s and Conan O’Brien’s talk shows by decades.